Powder culture media are very complex mixtures of dozens of components. Analysing for quality assurance and as a PAT tool to correlate fermentation properties with the medium used is a huge challenge for chromatography, but straightforward for imaging spectroscopy.
Using the H2OPTX system the powder is simply placed in a sample cup and placed in the Platerator Raman imaging system. This produces an image where particles may be identified by it's Raman spectrum and image analysis yields the amount of each component.
Raman image of culture media
Raman Image of Culture Medium